Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 7/20 | 0.64 |
| ▸ | UQCRB | P14927 | 4/20 | 0.61 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808090 | 0.86 | HKDC1 (0.61) | HSP90AA1RECQL | |
| SCHEMBL16187950 | 0.82 | MEN1 (0.58) | HSP90AA1HSP90AB1RECQL | |
| SCHEMBL16187949 | 0.82 | KMT2A (0.60) | GLO1PGAM1RECQL | |
| SCHEMBL11414744 | 0.80 | NFKBIA (0.56) | HSD17B2HSP90AA1CA2RECQL | |
| SCHEMBL16187974 | 0.78 | HSD17B2 (0.67) | HSD17B2UQCRBPSDCA1CA2 | |
| SCHEMBL9351736 | 0.77 | KEAP1 (0.65) | GLO1 | |
| SCHEMBL7537943 | 0.77 | RECQL (0.76) | UQCRBRECQL | |
| SCHEMBL10013444 | 0.76 | HSD17B2 (0.61) | HSD17B2UQCRBPSDCA1CA2 | |
| SCHEMBL15121247 | 0.76 | HSD17B2 (0.64) | HSD17B2UQCRBPSD | |
| SCHEMBL7587850 | 0.76 | HSD17B2 (0.79) | HSD17B2UQCRBPSDGLO1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | disclosed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | disclosed |
| WO-2012036512-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | 연세대학교 산학협력단 (KR) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | COL2A1, MYADM, COL1A1 | HSD17B2 1664/4885UQCRB 1884/4885PSD 3592/4885 |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | COL2A1, MYADM, COL1A1 | HSD17B2 1551/4885UQCRB 1624/4885PSD 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.