Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 9/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45795 | 0.88 | CHRM3 (0.49) | CHRM3IDO1WDR5TP53 | |
| SCHEMBL44645 | 0.83 | WDR5 (0.51) | WDR5 | |
| SCHEMBL13844857 | 0.83 | WDR5 (0.51) | CHRM3WDR5TP53 | |
| SCHEMBL44750 | 0.82 | CYP1A2 (0.41) | TP53 | |
| SCHEMBL44862 | 0.80 | GAA (0.47) | WDR5TP53 | |
| SCHEMBL44675 | 0.80 | ALDH1A1 (0.53) | WDR5 | |
| SCHEMBL45277 | 0.79 | TP53 (0.49) | WDR5EPHX2TP53 | |
| SCHEMBL38543 | 0.78 | WDR5 (0.45) | WDR5 | |
| SCHEMBL44495 | 0.78 | WDR5 (0.55) | WDR5 | |
| SCHEMBL44054 | 0.77 | MAPT (0.53) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | claimed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |