Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247046 | 0.91 | SLC6A3 (0.37) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL13247045 | 0.88 | SLC6A3 (0.42) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL13247044 | 0.85 | MAPT (0.45) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL700313 | 0.82 | ADRA2A (0.49) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL13247010 | 0.81 | ADRA2A (0.45) | KDM4EMAPTSLC6A2CYP3A4POLB | |
| SCHEMBL10000101 | 0.80 | PSMD14 (0.39) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL13247041 | 0.74 | ADRA2A (0.46) | KDM4EMAPTSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13247040 | 0.73 | ADRA2A (0.45) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL16060314 | 0.72 | SLC6A3 (0.65) | KDM4EALDH1A1MAPTSLC6A3SLC6A2 | |
| SCHEMBL16154381 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1MAPTCYP3A4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124774-B2 | Therapeutic ((phenyl)imidazolyl)methylquinolinyl compounds | ALLERGAN, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100197729-A1 | THERAPEUTIC ((PHENYL)IMIDAZOLYL)METHYLQUINOLINYL COMPOUNDS | ALLERDAN, INC. (US) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197729-A1 | THERAPEUTIC ((PHENYL)IMIDAZOLYL)METHYLQUINOLINYL COMPOUNDS | GOT2, COQ8A, OAT | KDM4E 3202/4885ALDH1A1 1578/4885MAPT 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.