Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 15/20 | 0.74 |
| ▸ | GSTA1 | P08263 | 9/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.74 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.74 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.74 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.74 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031690 | 0.90 | GSTP1 (0.71) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL10001192 | 0.88 | GSTP1 (0.56) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL9108011 | 0.85 | GSTP1 (1.00) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL10031684 | 0.85 | GSTP1 (0.80) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL3713736 | 0.85 | GSTP1 (0.80) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL10014667 | 0.85 | GSTP1 (0.80) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL26353 | 0.85 | GSTP1 (1.00) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL29384243 | 0.85 | GSTP1 (1.00) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL22260541 | 0.85 | GSTP1 (0.71) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL3713733 | 0.84 | GSTP1 (0.97) | GSTP1GSTA1MEN1ABCC3PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056284-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230058971-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-11548861-B2 | Drugs and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11160870-B2 | Extended release microparticles and suspensions thereof for medical therapy | Graybug Vision, Inc. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200230246-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2020-07-23 | — | — | US | disclosed |
| US-10557853-B2 | Molecular sensor and methods of use thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-02-11 | — | — | US | disclosed |
| US-20200031783-A1 | DRUGS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | Graybug Vision, Inc. (US) | 2020-01-30 | — | — | US | disclosed |
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9956302-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180110864-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | Graybug Vision, Inc. (US) | 2018-04-26 | — | — | US | disclosed |
| US-9808531-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170307625-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-10-26 | — | — | US | disclosed |
| US-20170307625-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-10-26 | — | — | US | disclosed |
| US-9696310-B2 | Molecular sensor and methods of use thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-04 | — | — | US | disclosed |
| US-9696310-B2 | Molecular sensor and methods of use thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-04 | — | — | US | disclosed |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | Graybug Vision, Inc. (US) | 2017-03-23 | — | — | US | disclosed |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | Graybug Vision, Inc. (US) | 2017-03-23 | — | — | US | disclosed |
| US-20150276753-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-10-01 | — | — | US | disclosed |
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031783-A1 | DRUGS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | PDE6C, PDE6A, PDE6D | GSTP1 954/4885GSTA1 1319/4885MEN1 3568/4885 |
| US-11548861-B2 | Drugs and compositions for the treatment of ocular disorders | PDE6C, PDE6A, PDE6D | GSTP1 954/4885GSTA1 1319/4885MEN1 3568/4885 |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | PTGIR, PTGIS, CA2 | GSTP1 1900/4885GSTA1 2248/4885MEN1 3138/4885 |
| US-20150276753-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | MAVS, STIM1, HSPE1 | GSTP1 2603/4885GSTA1 2413/4885MEN1 3881/4885 |
| US-20170307625-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | MAVS, STIM1, HSPE1 | GSTP1 2603/4885GSTA1 2413/4885MEN1 3881/4885 |
| US-11160870-B2 | Extended release microparticles and suspensions thereof for medical therapy | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20230058971-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20200230246-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20180110864-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | PTGIR, PTGIS, CA2 | GSTP1 1900/4885GSTA1 2248/4885MEN1 3138/4885 |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | CYP4F2, ACR, CYP4F3 | GSTP1 33/4885GSTA1 78/4885MEN1 3297/4885 |
| US-20230056284-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-10557853-B2 | Molecular sensor and methods of use thereof | MAVS, STIM1, HSPE1 | GSTP1 2603/4885GSTA1 2413/4885MEN1 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.