SCHEMBL10001936

SCHEMBL10001936

Cc1cc(NC(=O)CN(CCN2CCOCCN(CCN(CC(=O)O)CC(=O)NC(CSS(C)(=O)=O)C(=O)O)CC2)CC(=O)O)cc2[nH]c(=O)ccc12

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.39
▸ TNKS2 Q9H2K2 1/20 0.36
▸ CASR P41180 5/20 0.35
▸ TSHR P16473 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ USP2 O75604 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ CHRM3 P20309 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14530618 0.90 TERT (0.39) TERTTNKS2CASRTSHRRAB9A
SCHEMBL10035653 0.83 TERT (0.54) TERTTNKS2TSHRRAB9ALMNA
SCHEMBL10035654 0.82 TERT (0.55) TERTTNKS2TSHRRAB9AALDH1A1
SCHEMBL10001923 0.80 TERT (0.41) TERTTNKS2CASRTSHRRAB9A
SCHEMBL10001924 0.78 TERT (0.41) TERTTNKS2TSHRRAB9AALDH1A1
SCHEMBL10001931 0.77 TERT (0.51) TERTTNKS2TSHRRAB9ALMNA
SCHEMBL10001935 0.77 TERT (0.47) TERTTNKS2CASRTSHRLMNA
SCHEMBL10001937 0.76 CASR (0.31) CASR
SCHEMBL10001921 0.76 TERT (0.48) TERTTNKS2CASRTSHRALDH1A1
SCHEMBL10001934 0.74 TERT (0.49) TERTTNKS2TSHRRAB9AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299675-A1 Luminescent Lanthanide Binding Chelates HLCS, LYAR, SLC6A13 TERT 2908/4885TNKS2 3224/4885CASR 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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