SCHEMBL10035702

SCHEMBL10035702

Cc1cc(=O)[nH]c2cc(NC(=O)CN(CC=O)CCN(CC=O)CCN(CC=O)CC(=O)NNC(=O)CCN3C(=O)C=CC3=O)ccc12

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 17/20 0.39
▸ HPGD P15428 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ GLA P06280 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001927 0.88 TERT (0.40) TERT
SCHEMBL10035607 0.82 TERT (0.50) TERTHPGDALDH1A1CYP2C9
SCHEMBL10001934 0.82 TERT (0.49) TERTHPGD
SCHEMBL14367687 0.73 TERT (0.48) TERTHPGDKDM4EALDH1A1GLA
SCHEMBL19274957 0.73 TERT (0.33) TERTHPGDKDM4EALDH1A1GLA
SCHEMBL13273544 0.70 CA1 (0.46) TERTHPGDLMNACYP2C9
SCHEMBL23130692 0.69 TERT (0.43) TERTHPGDKDM4EALDH1A1GLA
SCHEMBL10035654 0.68 TERT (0.55) TERTALDH1A1LMNA
SCHEMBL10035653 0.68 TERT (0.54) TERTLMNA
SCHEMBL7923976 0.67 KDM4E (0.53) TERTHPGDKDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299675-A1 Luminescent Lanthanide Binding Chelates HLCS, LYAR, SLC6A13 TERT 2908/4885HPGD 3474/4885KDM4E 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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