SCHEMBL24112159

SCHEMBL24112159

C/C=C1\C(=N)Oc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 1/20 0.36
TOP2A P11388 1/20 0.36
MAPK1 P28482 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
ACHE P22303 2/20 0.33
STK17B O94768 2/20 0.33
MIF P14174 1/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
MCL1 Q07820 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SETD7 Q8WTS6 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
MAOA P21397 3/20 0.31
MAOB P27338 3/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10005481 0.83 MAPK1 (0.43) TOP1TOP2AMAPK1KDM4EATM
SCHEMBL19659080 0.73 MAPK1 (0.36) TOP1TOP2AMAPK1KDM4EATM
SCHEMBL15160874 0.71 ALDH1A1 (0.57) TOP1TOP2AACHESTK17BMIF
SCHEMBL16385020 0.68 KDM4E (0.38) MAPK1KDM4EATMACHESTK17B
SCHEMBL4522727 0.66 MAPK1 (0.43) TOP1TOP2AMAPK1KDM4EATM
SCHEMBL599045 0.65 DRD2 (0.43) MAPK1KDM4EATMMEN1ALDH1A1
SCHEMBL16382602 0.64 KDM4E (0.35) MAPK1KDM4EATMACHESTK17B
SCHEMBL16382448 0.64 KDM4E (0.35) MAPK1KDM4EATMACHESTK17B
SCHEMBL9421104 0.63 TOP1 (0.38) TOP1TOP2AMAPK1KDM4EATM
SCHEMBL9421095 0.63 TOP1 (0.38) TOP1TOP2AMAPK1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220037599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-03 US disclosed
US-20210391548-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220037599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, TLL1, TLL2 TOP1 2810/4885TOP2A 4080/4885MAPK1 1660/4885
US-20210391548-A1 ORGANIC LIGHT-EMITTING DEVICE OR51E2, OR10J3, LEF1 TOP1 2809/4885TOP2A 4053/4885MAPK1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.