Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325069 | 0.78 | LMNA (0.50) | DRD2DRD4MEN1KMT2AMAPT | |
| SCHEMBL18557051 | 0.77 | MYC (0.40) | DRD2DRD4SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL23095433 | 0.76 | MAPT (0.54) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL10005481 | 0.76 | MAPK1 (0.43) | DRD2DRD4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4558454 | 0.76 | ALDH1A1 (0.44) | DRD2MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8859036 | 0.76 | CES1 (0.56) | DRD2DRD4CYP19A1CYP11B2MEN1 | |
| SCHEMBL8676274 | 0.76 | CYP19A1 (0.46) | CYP19A1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL19336216 | 0.75 | MAPT (0.52) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL8218246 | 0.75 | TRPA1 (0.49) | DRD2DRD4MAPTHTTSMN1; SMN2 | |
| SCHEMBL1104624 | 0.75 | MAPT (0.58) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400972-B1 | Fluorescent degree of cure monitors | MINNESOTA MINING & MFG (US) | 1996-07-03 | — | — | EP | claimed |
| US-5182316-A | Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-01-26 | — | — | US | claimed |
| US-5047444-A | Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-10 | — | — | US | claimed |
| EP-0400972-A2 | Fluorescent degree of cure monitors | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-05 | — | — | EP | claimed |
| US-20120074336-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) | 2012-03-29 | — | — | US | disclosed |
| US-8114997-B2 | N4-acylcytosine nucleosides for treatment of viral infections | PHARMASSET, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-7964722-B2 | Light-driven rotary molecular motors | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | NATIONAL SCIENCE FOUNDATION | 2011-03-31 | — | — | US | disclosed |
| US-RE42015-E1 | N4-acylcytosine-1,3-dioxolane nucleosides for treatment of viral infections | PHARMASSET, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| EP-2091094-A2 | Organic light-emitting element | Yamagata Promotional Organization for Industrial Technology (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-20090176730-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET, INC. (US) | 2009-07-09 | — | — | US | disclosed |
| EP-1569652-A4 | N SP 4 /SP-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | PHARMASSET INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-0642483-A4 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF. | — | 1995-04-19 | — | — | EP | disclosed |
| EP-0642483-A1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5227560-A | Vinylene or exomethylene groups from active methine compounds | THE DOW CHEMICAL COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1993009078-A1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| US-5182316-A | Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| US-5118559-A | Dibenzofulvene compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5047444-A | Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0400972-A2 | Fluorescent degree of cure monitors | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176730-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | ENTPD5, NT5C3B, PNP | DRD2 1250/4885DRD4 440/4885CYP19A1 3276/4885 |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | CCNA2, CCNO, SCO2 | DRD2 1087/4885DRD4 1823/4885CYP19A1 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.