SCHEMBL10014872

SCHEMBL10014872

c1ccc(-n2c3ccccc3n(-c3ccccc3)c3cc4c(cc32)n(-c2ccccc2)c2ccccc2n4-c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.64
KDM4E B2RXH2 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 2/20 0.43
HTT P42858 2/20 0.43
HSD17B10 Q99714 1/20 0.43
GSK3A P49840 3/20 0.42
GSK3B P49841 3/20 0.42
GAA P10253 2/20 0.42
PGR P06401 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
NOTUM Q6P988 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062115 0.85 L3MBTL1 (0.67) ATMKDM4EL3MBTL1ALDH1A1TSHR
SCHEMBL20062260 0.85 L3MBTL1 (0.67) ATMKDM4EL3MBTL1ALDH1A1TSHR
SCHEMBL16850159 0.82 L3MBTL1 (0.75) ATMKDM4EL3MBTL1ALDH1A1TSHR
SCHEMBL10621020 0.81 L3MBTL1 (0.95) ATMKDM4EL3MBTL1ALDH1A1MAPK1
SCHEMBL6569796 0.79 L3MBTL1 (0.78) ATMKDM4EL3MBTL1ALDH1A1TSHR
SCHEMBL30402523 0.79 L3MBTL1 (0.78) ATMKDM4EL3MBTL1ALDH1A1TSHR
SCHEMBL29358118 0.78 L3MBTL1 (1.00) ATMKDM4EL3MBTL1ALDH1A1MAPK1
SCHEMBL31962 0.78 L3MBTL1 (1.00) ATMKDM4EL3MBTL1ALDH1A1MAPK1
Benzene SCHEMBL28486033 0.78 L3MBTL1 (1.00) ATMKDM4EL3MBTL1ALDH1A1MAPK1
SCHEMBL10027594 0.77 L3MBTL1 (0.75) ATMKDM4EL3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334384-B2 Process for preparing tetrahydrotetraazapentacenes and derivatives XEROX CORPORATION (US) 2012-12-18 US disclosed
US-8334384-B2 Process for preparing tetrahydrotetraazapentacenes and derivatives XEROX CORPORATION (US) 2012-12-18 US disclosed
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS CYP4Z1, TCF4, TERT ATM 2442/4885KDM4E 582/4885L3MBTL1 2598/4885
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES DHPS, TBXA2R, DHRS9 ATM 2032/4885KDM4E 691/4885L3MBTL1 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.