Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016135 | 0.75 | POLB (0.38) | CRHR1TP53POLBTHRBRAPGEF4 | |
| SCHEMBL340223 | 0.74 | MDM2 (0.36) | TP53LMNA | |
| SCHEMBL21248111 | 0.68 | SLC40A1 (0.45) | TP53LMNAPOLB | |
| SCHEMBL10049500 | 0.67 | GLA (0.30) | SOAT2SOAT1 | |
| SCHEMBL1642899 | 0.64 | GLO1 (0.47) | TP53THRBL3MBTL1 | |
| SCHEMBL21778151 | 0.63 | GABRA1 (0.38) | TP53LMNA | |
| SCHEMBL10016134 | 0.62 | RAB9A (0.47) | TP53LMNAPOLBTHRB | |
| SCHEMBL23499841 | 0.60 | ALDH1A1 (0.39) | TP53LMNAPOLBL3MBTL1 | |
| SCHEMBL14632564 | 0.60 | PLAU (0.37) | TP53LMNA | |
| SCHEMBL1005996 | 0.60 | ALDH1A1 (0.38) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016092-A1 | Catalysts based on quinoline precursors | BASELL POLYOLEFINE GMBH (DE) | 2012-01-19 | — | — | US | disclosed |