Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632500 | 0.81 | CCR4 (0.34) | NFKBIARELAGLO1SLC40A1AGTR1 | |
| SCHEMBL21248111 | 0.79 | SLC40A1 (0.45) | PLAUNFKBIARELAGLO1MAPT | |
| SCHEMBL1005996 | 0.78 | ALDH1A1 (0.38) | MAPTKDM4ELMNASLC40A1SMN1; SMN2 | |
| SCHEMBL21778151 | 0.76 | GABRA1 (0.38) | PLAUGLO1MAPTLMNASLC40A1 | |
| SCHEMBL2286780 | 0.73 | TDP1 (0.52) | NFKBIAGLO1MAPTKDM4ELMNA | |
| SCHEMBL21772242 | 0.72 | CCR4 (0.35) | PLAUNFKBIARELAGLO1KDM4E | |
| SCHEMBL14632639 | 0.70 | LMNA (0.41) | MAPTKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL23499841 | 0.70 | ALDH1A1 (0.39) | MAPTKDM4ELMNAHTTPAX8 | |
| SCHEMBL21772221 | 0.69 | PTK2 (0.33) | LMNASMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL14632443 | 0.69 | BACE1 (0.56) | PLAUNFKBIARELAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023635-A1 | CATALYSTS BASED ON HETEROCYCLIC-8-ANILINOQUINOLINE LIGANDS | EQUISTAR CHEMICALS, LP | 2013-01-24 | — | — | US | disclosed |
| US-20130023635-A1 | CATALYSTS BASED ON HETEROCYCLIC-8-ANILINOQUINOLINE LIGANDS | EQUISTAR CHEMICALS, LP | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023635-A1 | CATALYSTS BASED ON HETEROCYCLIC-8-ANILINOQUINOLINE LIGANDS | TLR7, LENG8, TLR8 | PLAU 2021/4885NFKBIA 608/4885RELA 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.