Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.46 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.46 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15205218 | 1.00 | TAS1R3 (0.57) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL15205094 | 1.00 | TAS1R3 (0.57) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL12923993 | 0.92 | TAS1R3 (0.57) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL15205233 | 0.87 | TAS1R3 (0.75) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL10016643 | 0.87 | TAS1R3 (0.75) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL22225439 | 0.84 | TAS1R3 (0.45) | TAS1R3TAS1R1CNR1CNR2FFAR1 | |
| SCHEMBL8036368 | 0.80 | CNR1 (0.53) | TAS1R3TAS1R1PSMB11PSMA7PSMB1 | |
| SCHEMBL9467871 | 0.79 | TAS1R3 (0.42) | TAS1R3TAS1R1 | |
| SCHEMBL6514878 | 0.79 | ZDHHC20 (0.51) | FFAR1 | |
| SCHEMBL9314536 | 0.79 | ZDHHC20 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636666-B1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | NAGOYA INDUSTRIAL SCIENCE RES INSTITUTE (JP) | 2018-01-10 | — | — | EP | disclosed |
| CN-103189350-B | Trans-2-decenoic acid derivative and drug containing same | NAGOYA INDUSTRIAL SCIENCE RESRARCH INSTITUTE (JP) | 2016-04-27 | — | — | CN | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2842553-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2842553-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2636666-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | Nagoya Industrial Science Research Institute (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| CN-103189350-A | Trans-2-decenoic acid derivative and drug containing same | NAGOYA IND SCIENCE RES INST | 2013-07-03 | — | — | CN | disclosed |
| WO-2012060396-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | 財団法人名古屋産業科学研究所 (JP) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297562-A1 | ANALGESIC | OPRK1, OPRL1, OPRD1 | TAS1R3 2987/4885TAS1R1 3106/4885PSMB11 4056/4885 |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | BDNF, NTRK2, NGF | TAS1R3 4070/4885TAS1R1 3996/4885PSMB11 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.