Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28484359 | 0.86 | FNTA (0.60) | MAPTALDH1A1KDM4ETHRBALOX12 | |
| SCHEMBL29888965 | 0.86 | FNTA (0.60) | MAPTALDH1A1KDM4ETHRBALOX12 | |
| SCHEMBL10018565 | 0.82 | AMY1A (0.57) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL10018555 | 0.81 | VCAM1 (0.48) | MAPTALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL10018564 | 0.80 | MAPT (0.52) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL7262437 | 0.80 | MAPT (0.48) | MAPTALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL7262434 | 0.80 | MAPT (0.48) | MAPTALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL10018561 | 0.77 | MAPT (0.55) | MAPTALDH1A1KDM4ETHRBTDP1 | |
| SCHEMBL13726645 | 0.77 | FNTA (0.55) | MAPTALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL13726644 | 0.77 | FNTA (0.55) | MAPTALDH1A1TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178749-A1 | NS1 PROTEIN INHIBITORS | ROTH MICHAEL (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120178749-A1 | NS1 PROTEIN INHIBITORS | ROTH MICHAEL (US) | 2012-07-12 | — | — | US | disclosed |
| US-8119656-B2 | Inhibitors of the influenza virus non-structural 1 protein | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119656-B2 | Inhibitors of the influenza virus non-structural 1 protein | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090170840-A1 | NS1 protein inhibitors | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |
| US-20090170840-A1 | NS1 protein inhibitors | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170840-A1 | NS1 protein inhibitors | MAVS, SERPINB1, SPINT2 | MAPT 2783/4885ALDH1A1 3348/4885KDM4E 2872/4885 |
| US-20120178749-A1 | NS1 PROTEIN INHIBITORS | MAVS, SERPINB1, SPINT2 | MAPT 2783/4885ALDH1A1 3348/4885KDM4E 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.