SCHEMBL10022967

SCHEMBL10022967

CC1c2ccccc2-c2cccc(-c3ccc(CO)cc3)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
PDCD1 Q15116 6/20 0.38
CD274 Q9NZQ7 6/20 0.38
TSHR P16473 1/20 0.36
BAZ2B Q9UIF8 1/20 0.35
BAZ2A Q9UIF9 1/20 0.35
PDK2 Q15119 1/20 0.35
FYN P06241 1/20 0.34
LTA4H P09960 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
APP P05067 1/20 0.32
SNCA P37840 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022975 0.76 DRD1 (0.48) DRD2DRD1CHRNB2CHRNA4
SCHEMBL31121357 0.71 PGR (0.41) TSHR
Methyl Alcohol SCHEMBL14815699 0.70 ALDH1A1 (0.38) EDNRBEDNRAACHE
SCHEMBL358532 0.70 GPR3 (0.39) TSHRACHE
SCHEMBL31338566 0.70 GPR3 (0.39) TSHRACHE
Hydrochloric Acid SCHEMBL28225814 0.70 GPR3 (0.39) DRD2DRD1BCHEACHE
SCHEMBL35773 0.68 TSHR (0.62) MKNK1MKNK2PDCD1CD274TSHR
SCHEMBL28807674 0.68 GPR3 (0.38) DRD2DRD1BCHEACHE
SCHEMBL30987013 0.68 ALDH1A1 (0.41) TSHRDRD1ACHE
SCHEMBL29285278 0.68 ALDH1A1 (0.41) TSHRDRD1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932797-B2 Photoacid generators DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-8907122-B2 Method of preparing photoacid generating monomer ROHM AND HAAS ELECTRONIC MATERIAL LLC (US) 2014-12-09 US disclosed
US-8716518-B2 Photoacid generating monomer and precursor thereof ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-05-06 US disclosed
US-20120172619-A1 METHOD OF PREPARING PHOTOACID GENERATING MONOMER ROHM AND HAAS ELECTRONIC MATERIALS LLC 2012-07-05 US disclosed
US-20120172555-A1 PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF DOW GLOBAL TECHNOLOGIES LLC 2012-07-05 US disclosed
US-20120141939-A1 PHOTOACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120141939-A1 PHOTOACID GENERATORS F10, GNG2, H1-0 MKNK1 4401/4885MKNK2 4083/4885PDCD1 4855/4885
US-20120172555-A1 PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF SULT1A1, SULT1E1, SULT2A1 MKNK1 3945/4885MKNK2 3884/4885PDCD1 4799/4885
US-20120172619-A1 METHOD OF PREPARING PHOTOACID GENERATING MONOMER POLL, SULT1A1, SULT1E1 MKNK1 3502/4885MKNK2 3058/4885PDCD1 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.