Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 3/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289026 | 0.86 | XDH (0.49) | RXRBRXRAXDHSLC22A12 | |
| SCHEMBL29771992 | 0.84 | RXRB (0.70) | RXRBRXRARARBMCL1HNF4A | |
| SCHEMBL1498034 | 0.84 | RXRB (0.70) | RXRBRXRARARBMCL1HNF4A | |
| Hydrochloric Acid SCHEMBL4365452 | 0.82 | RXRB (0.68) | RXRBRXRARARBMCL1HNF4A | |
| Hydrochloric Acid SCHEMBL9150803 | 0.82 | RXRB (0.68) | RXRBRXRARARBMCL1HNF4A | |
| SCHEMBL28246462 | 0.81 | MCL1 (0.50) | XDHSLC22A12MCL1PTGER4MAP4K4 | |
| SCHEMBL13522888 | 0.80 | ACMSD (0.63) | RXRBRXRARARBMCL1HNF4A | |
| SCHEMBL8840571 | 0.80 | MCL1 (0.65) | RXRBRXRAXDHSLC22A12RARB | |
| SCHEMBL122517 | 0.80 | ACMSD (0.63) | RXRBRXRARARBMCL1HNF4A | |
| SCHEMBL8960674 | 0.80 | RXRB (0.62) | RXRBRXRARARBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | FAS SECURED CREDITORS HOLDCO, LLC | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | LCAT, DGAT2, SOAT2 | RXRB 3198/4885RXRA 3267/4885XDH 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.