Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.52 |
| ▸ | GABRD | O14764 | 20/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.52 |
| ▸ | GABRE | P78334 | 20/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12993977 | 0.88 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12630585 | 0.85 | GABRB3 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12473393 | 0.84 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7086645 | 0.83 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055617 | 0.82 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL33214 | 0.81 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14043505 | 0.81 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4751430 | 0.80 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL44222 | 0.79 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL15088 | 0.79 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097603-B2 | Compositions for controlling parasites on animals | BAYER ANIMAL HEALTH GMBH (DE) | 2012-01-17 | — | — | US | disclosed |
| US-7939565-B2 | N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide and one or more of tebufenozide, deltamethrin,ethiprole, fipronil, indoxacarb, emamectin-benzoate, abamectin, spinosad | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20080214634-A1 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
| US-7288572-B2 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20070015835-A1 | Active substance combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214634-A1 | Active substance combinations having insecticidal and acaricidal properties | ACHE, DDT, AADAC | GABRP 447/4885GABRD 2472/4885GABRA1 1753/4885 |
| US-20070015835-A1 | Active substance combinations having insecticidal and acaricidal properties | ACHE, DDT, AADAC | GABRP 447/4885GABRD 2472/4885GABRA1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.