Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 4/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047464 | 1.00 | LPAR1 (0.45) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047460 | 1.00 | LPAR1 (0.45) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047466 | 0.97 | LPAR1 (0.47) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047468 | 0.97 | LPAR1 (0.47) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047457 | 0.93 | TSHR (0.43) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047469 | 0.91 | LPAR1 (0.51) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL10028014 | 0.91 | LPAR1 (0.51) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12301810 | 0.89 | HSD17B10 (0.46) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12301812 | 0.88 | TDP1 (0.42) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047461 | 0.88 | LPAR1 (0.42) | LPAR1LPAR3LPAR2TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315826-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | BELROSE PHARMA, INC. (US) | 2014-10-23 | — | — | US | disclosed |
| US-8367065-B2 | Targeted polymeric prodrugs containing multifunctional linkers | ENZON PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110230420-A1 | RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS | ENZON PHARMACEUTICALS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230420-A1 | RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS | PHAX, KPNA6, KPNA2 | LPAR1 1037/4885LPAR3 959/4885LPAR2 829/4885 |
| US-20140315826-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | C9, SERPINC1, C1R | LPAR1 1354/4885LPAR3 1946/4885LPAR2 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.