SCHEMBL28265249

SCHEMBL28265249

CCOC(=O)C(F)n1cccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MMP8 P22894 1/20 0.34
MAPK1 P28482 1/20 0.34
GAA P10253 2/20 0.33
LPO P22079 2/20 0.33
ALOX15 P16050 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8906464 0.79 PIN1 (0.39) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL10028356 0.79 MAPT (0.40) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL28245313 0.77 ALDH1A1 (0.45) ALDH1A1RAB9A
SCHEMBL26660824 0.77 CYP26A1 (0.41) MEN1KMT2AALDH1A1KDM4EHSD17B10
SCHEMBL27508846 0.74 PIN1 (0.40) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL17111315 0.74 ALDH1A1 (0.38) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL13284366 0.72 SMN1; SMN2 (0.41) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL5972394 0.72 MEN1 (0.40) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL27455916 0.72 PIN1 (0.34) PIN1MEN1NPC1KMT2AALDH1A1
SCHEMBL9091102 0.69 LMNA (0.38) PIN1MEN1NPC1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180570-A A kind of preparation method of trichlopyr fourth 2-ethoxyethyl acetate 湖北犇星农化有限责任公司 2019-01-11 CN disclosed