SCHEMBL10028634

SCHEMBL10028634

C=C(C)C1CCC(C)CC1CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 1/20 0.41
SLC1A2 P43004 1/20 0.41
THPO P40225 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
GRIK1 P39086 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
BLM P54132 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRIK3 Q13003 1/20 0.41
GRIK4 Q16099 1/20 0.41
GRIK5 Q16478 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9950894 1.00 MEN1 (0.41) MEN1KMT2AMAPK1TSHRSLC1A2
SCHEMBL9951261 0.86 EPHX1 (0.35) MEN1KMT2AMAPK1TSHRSLC1A2
SCHEMBL9951259 0.86 EPHX1 (0.35) MEN1KMT2AMAPK1TSHRSLC1A2
SCHEMBL10028632 0.81 TRPM8 (0.37) EPHX1TRPM8
SCHEMBL693647 0.81 TRPM8 (0.34) ALDH1A1EPHX1TRPM8
SCHEMBL26191630 0.77 ALOX15 (0.31) ALDH1A1
SCHEMBL21504620 0.77 ALOX15 (0.31) ALDH1A1
SCHEMBL4762960 0.77 ALOX15 (0.31) ALDH1A1
SCHEMBL3276755 0.77 EPHX1 (0.35) EPHX1CES2TRPM8
SCHEMBL699177 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106742373-B A kind of automatic charging packaging facilities and its working method based on the exploitation of functional gingko milk beverage 徐州工程学院 2019-03-15 CN disclosed
US-20120165559-A1 Compounds Having a Physiological Effect V. MANE FILS (FR) 2012-06-28 US disclosed
US-20120165559-A1 Compounds Having a Physiological Effect V. MANE FILS (FR) 2012-06-28 US disclosed
WO-2010122239-A1 COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT V. MANE FILS (FR) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165559-A1 Compounds Having a Physiological Effect NPPA, CYP11B2, SHBG MEN1 199/4885KMT2A 4572/4885MAPK1 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.