Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951261 | 0.81 | EPHX1 (0.35) | TRPM8EPHX1ALDH1A1 | |
| SCHEMBL9951259 | 0.81 | EPHX1 (0.35) | TRPM8EPHX1ALDH1A1 | |
| SCHEMBL10028634 | 0.81 | MEN1 (0.41) | TRPM8EPHX1ALDH1A1 | |
| SCHEMBL9950894 | 0.81 | MEN1 (0.41) | TRPM8EPHX1ALDH1A1 | |
| SCHEMBL10028632 | 0.81 | TRPM8 (0.37) | TRPM8EPHX1TLR4 | |
| SCHEMBL3793761 | 0.75 | EPHX1 (0.47) | TRPM8EPHX1 | |
| SCHEMBL4762960 | 0.73 | ALOX15 (0.31) | ALDH1A1 | |
| SCHEMBL21504620 | 0.73 | ALOX15 (0.31) | ALDH1A1 | |
| SCHEMBL26191630 | 0.73 | ALOX15 (0.31) | ALDH1A1 | |
| SCHEMBL21019790 | 0.72 | ALDH1A1 (0.36) | TRPM8EPHX1ALDH1A1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | claimed |
| EP-2421820-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. Mane Fils (FR) | 2012-02-29 | — | — | EP | claimed |
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
| EP-2421820-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. Mane Fils (FR) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010122239-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. MANE FILS (FR) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010122239-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. MANE FILS (FR) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | NPPA, CYP11B2, SHBG | TRPM8 412/4885EPHX1 871/4885ALDH1A1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.