Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.64 |
| ▸ | CA12 | O43570 | 5/20 | 0.64 |
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | CA9 | Q16790 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 3/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029063 | 1.00 | MMP2 (0.64) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10029061 | 0.99 | MMP2 (0.63) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL11623917 | 0.86 | ALDH1A1 (0.82) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL11807867 | 0.86 | ALDH1A1 (0.82) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL11649813 | 0.86 | ALDH1A1 (0.82) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL20282176 | 0.86 | MMP2 (0.64) | MMP2CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11628667 | 0.85 | ALDH1A1 (0.79) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6671584 | 0.85 | ALDH1A1 (0.79) | CA1CA2ALDH1A1PKMKDM4E | |
| SCHEMBL24242630 | 0.84 | MMP2 (0.57) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2008353 | 0.82 | ALDH1A1 (0.64) | MMP2ALDH1A1PKMKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993544-B2 | Carbamoylphosphonates as inhibitors and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2015-03-31 | — | — | US | disclosed |
| US-8993544-B2 | Carbamoylphosphonates as inhibitors and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2015-03-31 | — | — | US | disclosed |
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-02-09 | — | — | US | disclosed |
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | MMP9, MMP26, MMP25 | MMP2 10/4885CA12 307/4885CA1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.