SCHEMBL9683157

SCHEMBL9683157

C=C(C)C(=O)OCCNc1nc(Cl)nc(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
KMT2A Q03164 4/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
POLB P06746 2/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
MAPK1 P28482 1/20 0.34
APEX1 P27695 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11295972 0.82 THRB (0.40) THRBTSHRLMNAHTTALDH1A1
SCHEMBL9913752 0.81 TSHR (0.53) THRBTSHRKMT2AHTTALDH1A1
SCHEMBL28667907 0.78 ALDH1A1 (0.47) THRBTSHRKMT2ALMNAHTT
SCHEMBL13137607 0.77 TSHR (0.42) THRBTSHRKMT2ALMNAHTT
SCHEMBL3674371 0.76 THRB (0.47) THRBTSHRHTTALDH1A1POLB
SCHEMBL10030480 0.75 KCNH3 (0.60)
SCHEMBL10030481 0.73 PAX8 (0.48) TSHRKMT2AHTTKDM4EALDH1A1
SCHEMBL22356333 0.73 SMN1; SMN2 (0.41) THRBTSHRKMT2ALMNAHTT
SCHEMBL10704579 0.73 KMT2A (0.43) KMT2ALMNACA12CA1CA2
SCHEMBL2557575 0.73 L3MBTL1 (0.45) THRBTSHRKMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5156771-A Comprising a metal powder, a binder of a homo- or copolymer of a substituted hydroxystyrene and a solvent; printed circuits; noise shield; durability; adhesion KAO CORPORATION (JP) 1992-10-20 US disclosed
US-5087646-A FORMULATIONS AND PROCESS FOR DRESSING LEATHER AND COATING TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed
EP-0400642-A2 Electrically conductive paste composition KAO CORPORATION (JP) 1990-12-05 EP disclosed
US-4206279-A COVALENTLY BONDED TO DYES OR DYE PRECURSORS EASTMAN KODAK COMPANY (US) 1980-06-03 US disclosed
US-4168976-A Photographic film units containing aza heterocyclic polymeric mordants EASTMAN KODAK COMPANY (US) 1979-09-25 US disclosed
US-4119680-A SULFONATE MONOMER, UNSATURATED DICARBOXYLIC ACIDS EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed