SCHEMBL10030583

SCHEMBL10030583

CCCCCC(=O)NCCCNC(=O)CCCCN(C)CCCN1CCN(C)CC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.52
FAAH O00519 3/20 0.44
USP2 O75604 1/20 0.44
OPRD1 P41143 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PAOX Q6QHF9 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CASP2 P42575 1/20 0.42
KDM5A P29375 4/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM5C P41229 1/20 0.41
KDM5B Q9UGL1 1/20 0.41
KMT2A Q03164 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
NAAA Q02083 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437935 0.86 FAAH (0.55) DNM1FAAHUSP2OPRD1TP53
SCHEMBL20998566 0.83 USP2 (0.56) FAAHUSP2OPRD1TP53SMN1; SMN2
SCHEMBL10722577 0.83 TP53 (0.58) DNM1FAAHUSP2OPRD1TP53
SCHEMBL5533634 0.82 FAAH (0.60) DNM1FAAHUSP2OPRD1TP53
SCHEMBL5531859 0.82 FAAH (0.60) DNM1FAAHUSP2OPRD1TP53
SCHEMBL10723379 0.82 FAAH (0.60) DNM1FAAHUSP2OPRD1TP53
SCHEMBL5524009 0.82 FAAH (0.60) DNM1FAAHUSP2OPRD1TP53
SCHEMBL5538333 0.82 FAAH (0.60) DNM1FAAHUSP2OPRD1TP53
SCHEMBL829043 0.81 DNM1 (0.57) DNM1TP53SMN1; SMN2PAOXALDH1A1
SCHEMBL23729446 0.81 CASP2 (0.56) DNM1FAAHUSP2OPRD1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110610-B2 Amine co-initiators for radiation curable compositions AGFA GRAPHICS N.V. (BE) 2012-02-07 US disclosed
US-20100048756-A1 NOVEL RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2010-02-25 US disclosed