Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.54 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001961 | 0.87 | NQO2 (0.59) | NQO2KDM4ECYP19A1ALDH1A1HPGD | |
| SCHEMBL28513249 | 0.82 | ALDH1A1 (0.46) | KDM4EEGFRALDH1A1MAOADYRK1A | |
| SCHEMBL30507409 | 0.82 | ALDH1A1 (0.59) | KDM4EEGFRALDH1A1MAOADYRK1A | |
| SCHEMBL8184169 | 0.82 | ALDH1A1 (0.59) | KDM4EEGFRALDH1A1MAOADYRK1A | |
| SCHEMBL30507425 | 0.82 | ALDH1A1 (0.46) | KDM4EEGFRALDH1A1MAOADYRK1A | |
| SCHEMBL12998226 | 0.80 | NQO2 (0.54) | NQO2KDM4ECYP19A1BRD9BRD7 | |
| SCHEMBL6608635 | 0.80 | AR (0.47) | KDM4EEGFRALDH1A1MAOADYRK1A | |
| SCHEMBL12002162 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1DYRK1AHPGDHSD17B10 | |
| SCHEMBL2797974 | 0.79 | CCNE2 (0.47) | KDM4EALDH1A1DYRK1AHPGDHSD17B10 | |
| SCHEMBL18288081 | 0.79 | L3MBTL1 (0.60) | KDM4EEGFRALDH1A1MAOADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408863-B1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORP (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9382425-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150031579-A1 | Aza-Benzazolium Containing Cyanine Dyes | MOLECULAR PROBES, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8883415-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2014-11-11 | — | — | US | disclosed |
| WO-2010107816-A2 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010107816-A2 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| US-20080044811-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2008-02-21 | — | — | US | disclosed |
| US-7226740-B2 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2007-06-05 | — | — | US | disclosed |
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | Life Technologies Corporation | 2004-07-15 | — | — | US | disclosed |
| US-6664047-B1 | Assymetrical; substituted by a cationic side chain; exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or with polypeptides | MOLECULAR PROBES, INC. | 2003-12-16 | — | — | US | disclosed |
| WO-2000066664-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | MOLECULAR PROBES, INC. (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | POLL, IK, ADAR | NQO2 1987/4885KDM4E 1578/4885CYP19A1 4702/4885 |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | POLRMT, POLB, POLL | NQO2 855/4885KDM4E 4619/4885CYP19A1 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.