Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031422 | 0.82 | NOS3 (0.36) | KMT2AMEN1NOS3NOS1ALDH1A1 | |
| SCHEMBL10064354 | 0.81 | NOS1 (0.39) | KMT2AMEN1NOS3NOS1ALDH1A1 | |
| SCHEMBL10064564 | 0.76 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL13790518 | 0.76 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL3910252 | 0.74 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL11192501 | 0.71 | MAOB (0.46) | ALDH1A1MAPTRECQLTSHRALOX15 | |
| SCHEMBL13035384 | 0.71 | NOS3 (0.39) | KMT2AMEN1NOS3NOS1ALDH1A1 | |
| SCHEMBL13790583 | 0.69 | KMT2A (0.55) | KMT2AMEN1NOS3NOS1ALDH1A1 | |
| SCHEMBL13871006 | 0.69 | NR1I2 (0.39) | ALDH1A1RECQLTSHRALOX15HSD17B10 | |
| SCHEMBL8607892 | 0.68 | NOS3 (0.36) | KMT2AMEN1NOS3NOS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632973-B2 | Methods for preparing aldehydes by self-aldol condensation | LOYOLA UNIVERSITY OF CHICAGO (US) | 2009-12-15 | — | — | US | disclosed |
| US-20090270658-A1 | Methods for preparing aldehydes by self-aldol condensation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270658-A1 | Methods for preparing aldehydes by self-aldol condensation | ADH1C, ALDH1A1, ADH1A | KMT2A 1240/4885MEN1 1300/4885NOS3 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.