Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003875 | 0.95 | ALDH1A1 (0.51) | SORT1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL18132518 | 0.73 | ALDH1A1 (0.72) | SORT1HSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL6707975 | 0.72 | MEN1 (0.51) | ALDH1A1KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL30281241 | 0.71 | ACMSD (0.40) | KDM4EKMT2AHTTHIF1A | |
| SCHEMBL20587999 | 0.71 | ACMSD (0.37) | KDM4EKMT2AHTTHIF1APOLB | |
| SCHEMBL19064374 | 0.70 | HSD17B10 (0.64) | HSD17B10ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL20172440 | 0.68 | MEN1 (0.53) | HSD17B10ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL20172442 | 0.68 | NAMPT (0.51) | SORT1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL15920569 | 0.67 | SORT1 (1.00) | SORT1MEN1KMT2ANAMPTCYP11B2 | |
| SCHEMBL3642636 | 0.66 | NAMPT (0.81) | NAMPTCYP11B2CYP11B1LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456308-A2 | PYRIDINE DERIVATIVES FOR CONTROLLING INVERTREBATE PESTS | BASF SE (DE) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011009804-A2 | PYRIDINE DERIVATIVES COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-27 | — | — | WO | disclosed |