Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033003 | 0.90 | EPHX2 (0.45) | EPHX2PTGESTAS2R14POLBALDH1A1 | |
| SCHEMBL1709408 | 0.86 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1709407 | 0.86 | TP53 (0.39) | EPHX2PTGESALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1709409 | 0.85 | POLB (0.38) | POLBSMN1; SMN2DGAT1KMT2A | |
| SCHEMBL1709480 | 0.85 | NPC1 (0.38) | ALDH1A1SMN1; SMN2DGAT1 | |
| SCHEMBL10033121 | 0.83 | USP30 (0.38) | TAS2R14KMT2AUSP30PTGDR2 | |
| SCHEMBL1709405 | 0.83 | TACR1 (0.38) | TRPM8DGAT1PTGDR2 | |
| SCHEMBL10032832 | 0.81 | TACR1 (0.36) | TRPM8DGAT1PTGDR2 | |
| SCHEMBL10032831 | 0.81 | TACR1 (0.36) | TRPM8DGAT1PTGDR2 | |
| SCHEMBL1709359 | 0.80 | USP30 (0.38) | ALDH1A1SMN1; SMN2DGAT1USP30PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |