Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709410 | 0.80 | POLB (0.35) | KMT2AMEN1 | |
| SCHEMBL1709408 | 0.75 | DGAT1 (0.38) | — | |
| SCHEMBL1709407 | 0.74 | TP53 (0.39) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1709409 | 0.74 | POLB (0.38) | KMT2AMEN1 | |
| SCHEMBL1709480 | 0.74 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL1709405 | 0.74 | TACR1 (0.38) | — | |
| SCHEMBL1709497 | 0.74 | EPHX2 (0.43) | KMT2AALDH1A1 | |
| SCHEMBL10033121 | 0.72 | USP30 (0.38) | KMT2A | |
| SCHEMBL10032831 | 0.72 | TACR1 (0.36) | — | |
| SCHEMBL10032832 | 0.72 | TACR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |