Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709398 | 0.89 | KDM1A (0.36) | USP30KDM1ATSHRNPC1RAB9A | |
| SCHEMBL1709408 | 0.87 | DGAT1 (0.38) | — | |
| SCHEMBL1709407 | 0.87 | TP53 (0.39) | NPC1RAB9AEPHX1KMT2APAX8 | |
| SCHEMBL1709409 | 0.86 | POLB (0.38) | RAB9AKMT2APAX8SIGMAR1 | |
| SCHEMBL1709480 | 0.86 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL1709497 | 0.83 | EPHX2 (0.43) | USP30PTGDR2KMT2ATAS2R14 | |
| SCHEMBL1709405 | 0.83 | TACR1 (0.38) | PTGDR2NAMPT | |
| SCHEMBL10032831 | 0.82 | TACR1 (0.36) | PTGDR2NAMPT | |
| SCHEMBL10032832 | 0.82 | TACR1 (0.36) | PTGDR2NAMPT | |
| SCHEMBL1709359 | 0.81 | USP30 (0.38) | USP30KDM1ANPC1RAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |