Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033100 | 0.88 | CYP11B1 (0.35) | PPOXALDH1A1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL10033128 | 0.83 | ALOX5AP (0.36) | ALDH1A1L3MBTL1KMT2AGAACYP11B1 | |
| SCHEMBL10033095 | 0.81 | L3MBTL1 (0.41) | PPOXALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10033131 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL10033112 | 0.80 | BRD4 (0.42) | ALDH1A1KMT2AGAAALOX5APFEN1 | |
| SCHEMBL10033098 | 0.79 | ALOX5AP (0.39) | ALDH1A1L3MBTL1GAACYP11B1CYP11B2 | |
| SCHEMBL10033113 | 0.78 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL10033106 | 0.78 | HTR2A (0.38) | ALDH1A1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL10033104 | 0.75 | MEN1 (0.38) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10033101 | 0.74 | ALDH1A1 (0.40) | ALDH1A1DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |