Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 5/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649410 | 0.90 | HTR6 (0.46) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL7916013 | 0.85 | CA1 (0.47) | CYP3A4IDO1TDO2HTR6CHRM4 | |
| SCHEMBL27827582 | 0.80 | KDM1A (0.50) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL13073826 | 0.80 | CYP3A4 (0.42) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL13698772 | 0.80 | CYP3A4 (0.42) | CYP3A4IDO1TDO2PNMTKDM1A | |
| Hydrochloric Acid SCHEMBL1005342 | 0.79 | KDM1A (0.49) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL14388811 | 0.78 | KDM1A (0.43) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL29649401 | 0.78 | HTR6 (0.55) | CYP3A4IDO1TDO2PNMTHTR6 | |
| SCHEMBL12828186 | 0.77 | PNMT (0.43) | CYP3A4IDO1TDO2PNMTKDM1A | |
| SCHEMBL13698768 | 0.77 | KDM1A (0.42) | CYP3A4IDO1TDO2PNMTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
| EP-2542524-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-01-09 | — | — | EP | disclosed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011107474-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | disclosed |
| US-20110039892-A1 | IMINOPYRIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-2269989-A1 | IMINOPYRIDINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ANXA2, ANXA3, ADM2 | CYP3A4 521/4885IDO1 34/4885TDO2 126/4885 |
| US-20110039892-A1 | IMINOPYRIDINE DERIVATIVE AND USE THEREOF | ADRA1D, ADRB1, ADRB2 | CYP3A4 1463/4885IDO1 62/4885TDO2 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.