SCHEMBL10036093

SCHEMBL10036093

CC(c1ccc2c(c1)C(=O)OC2=O)(c1ccc2c(c1)C(=O)OC2=O)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 2/20 0.41
CASP3 P42574 2/20 0.41
RAB9A P51151 2/20 0.41
SENP8 Q96LD8 2/20 0.41
SENP7 Q9BQF6 2/20 0.41
SENP6 Q9GZR1 2/20 0.41
PLA2G1B P04054 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NR1H2 P55055 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14865697 0.91 ALDH1A1 (0.35) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL18327992 0.91 ALDH1A1 (0.35) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL17118704 0.90 ALDH1A1 (0.39) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL16543901 0.89 ALDH1A1 (0.34) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL11887460 0.83 MAOA (0.41) ALDH1A1NPC1RAB9AL3MBTL1TDP1
SCHEMBL17943453 0.82 ALDH1A1 (0.41) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL12731650 0.81 ALOX15 (0.43) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL49774 0.81 ALOX15 (0.43) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL1545970 0.81 ALDH1A1 (0.60) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL16626117 0.81 ALOX15 (0.46) ALDH1A1NPC1CASP3RAB9ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228704-A1 MELT-PROCESSABLE POLYIMIDES WITH HIGH GLASS TRANSITION TEMPERATURE EVONIK FIBRES GMBH (AT) 2024-07-11 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11807730-B2 Composition for forming polyimide film for cover window, method for preparing the same, and use thereof SK INNOVATION CO., LTD. (KR) 2023-11-07 US disclosed
US-11795271-B2 Polyimide based film for cover window and display device comprising the same SK INNOVATION CO., LTD. (KR) 2023-10-24 US disclosed
US-11746184-B2 Polyimide-polyarylene polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-05 US disclosed
US-11680166-B2 Thermally stable and electrically isolating barrier film CORNING INCORPORATED (US) 2023-06-20 US disclosed
US-11676814-B2 Material for forming organic film, substrate for manufacturing semiconductor apparatus, method for forming organic film, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-13 US disclosed
US-11674920-B2 Moisture-sensitive film and sensor using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-13 US disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 WO disclosed
US-20110244202-A1 FLUOROPOLYIMIDE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2011-10-06 US disclosed
US-20110244247-A1 FLUOROPOLYIMIDE SINGLE LAYERED INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2011-10-06 US disclosed
US-20110196109-A1 POLYMER, COMPOSITION AND FILM SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-11 US disclosed
US-7989578-B2 Developable in aqueous alkaline solution; polyamides comprised of such as mono-2-hydroxyethyl acrylate derivatized pyromellitic acid and 4,4'-diaminodiphenyl ether; environmentally friendly ETERNAL CHEMICAL CO., LTD. (TW) 2011-08-02 US disclosed
US-20110137009-A1 POLYAMIC ACID, POLYIMIDE, MANUFACTURING METHOD THEREOF, AND POLYIMIDE FILM SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-06-09 US disclosed
US-20110076613-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND METHOD FOR PRODUCING THE SAME, AND RELIEF PRINTING PLATE AND METHOD FOR MAKING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076454-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING STARTING PLATE FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND RELIEF PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20100313752-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC TECHNOLOGIES PTY LTD (AU) 2010-12-16 US disclosed
US-20100086871-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2010-04-08 US disclosed
US-20080103275-A1 Negative photosensitive polyimide polymer and uses thereof ETERNAL CHEMICAL CO., LTD. 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746184-B2 Polyimide-polyarylene polymers PAICS, PIN1, PARN ALDH1A1 2532/4885NPC1 4727/4885CASP3 3507/4885
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT ALDH1A1 2452/4885NPC1 3034/4885CASP3 4149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.