SCHEMBL10036095

SCHEMBL10036095

O=Cc1cc(-c2cccc3c2C(=O)OC3=O)ccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.44
ERN1 O75460 4/20 0.39
BCL2L1 Q07817 1/20 0.37
BAD Q92934 1/20 0.37
HNF4A P41235 1/20 0.36
MCL1 Q07820 2/20 0.35
ACMSD Q8TDX5 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
SOS1 Q07889 1/20 0.35
HIF1A Q16665 1/20 0.35
FABP4 P15090 2/20 0.35
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 1/20 0.35
POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757811 0.84 TYMS (0.50) TYMSHNF4AMCL1ACMSDCYP1A2
SCHEMBL1709589 0.82 TYMS (0.44) TYMSERN1BCL2L1BADHNF4A
SCHEMBL14321815 0.77 TYMS (0.49) TYMSHNF4AMCL1ACMSDCYP1A2
SCHEMBL20344311 0.77 SLC6A3 (0.41) ERN1CYP1A2CYP2D6CYP2C9TSHR
SCHEMBL5177942 0.73 TTR (0.47) TYMSBCL2L1BADHNF4ATSHR
SCHEMBL12209848 0.73 TYMS (0.41) TYMSERN1TSHRALDH1A1L3MBTL1
SCHEMBL2591111 0.73 ACMSD (0.59) ERN1BCL2L1BADHNF4AMCL1
SCHEMBL617136 0.72 ALDH1A1 (0.56) TYMSHNF4ACYP2C9TSHRALDH1A1
SCHEMBL308375 0.72 TDP1 (0.52) TYMSHNF4ATSHRALDH1A1L3MBTL1
SCHEMBL31416073 0.72 TDP1 (0.52) TYMSHNF4ATSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263732-B2 Photo-alignment film and liquid crystal display element JNC CORPORATION (JP) 2012-09-11 US disclosed
US-8105752-B2 Photosensitive polyimides ETERNAL CHEMICAL CO., LTD. (TW) 2012-01-31 US disclosed
US-20100086871-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2010-04-08 US disclosed