Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.37 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.36 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916777 | 0.87 | HSD17B1 (0.47) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL9965558 | 0.82 | EP300 (0.33) | ESR1ESR2 | |
| SCHEMBL10035902 | 0.82 | ALOX5 (0.37) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL14838323 | 0.79 | HSD17B1 (0.41) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL10002017 | 0.79 | HSD17B1 (0.41) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL4184035 | 0.79 | PTP4A3 (0.36) | HSD17B1PTP4A3PTP4A2PTP4A1MEN1 | |
| SCHEMBL14838322 | 0.79 | HSD17B1 (0.43) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL12999573 | 0.78 | HSD17B1 (0.31) | HSD17B1PTP4A3 | |
| SCHEMBL20146996 | 0.77 | HSD17B1 (0.40) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 | |
| SCHEMBL16021787 | 0.77 | HSD17B1 (0.40) | HSD17B1PTP4A3PTP4A2PTP4A1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120044560-A9 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20100315693-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2010-12-16 | — | — | US | disclosed |