Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 5/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036561 | 0.94 | PARP10 (0.46) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL10036584 | 0.89 | KMT2A (0.45) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL10036580 | 0.89 | HTT (0.45) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL10036583 | 0.85 | PARP10 (0.47) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL12671969 | 0.84 | RAB9A (0.53) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL10036590 | 0.82 | ALDH1A1 (0.41) | PARP10NR4A2PTPRCPTPN2PTPN1 | |
| SCHEMBL10036585 | 0.81 | RXRA (0.47) | NR4A2MEN1KMT2AMAOBMAOA | |
| SCHEMBL12696220 | 0.79 | MAOB (0.43) | NR4A2PTPRCPTPN2PTPN1MAOB | |
| SCHEMBL10670934 | 0.78 | ALDH1A1 (0.52) | PTPN1MEN1KMT2ARXRARXRB | |
| SCHEMBL727046 | 0.78 | ALDH1A1 (0.52) | PTPN1MEN1KMT2ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120241373-A1 | COMPOSITE MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120012527-A1 | COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
| US-20100216899-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2010-08-26 | — | — | US | disclosed |
| WO-2010096563-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| US-20100216967-A1 | INTERFACIAL POLYMERIZATION METHODS FOR MAKING FLUOROALCOHOL-CONTAINING POLYAMIDES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-08-26 | — | — | US | disclosed |
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | IL2, IL6, TNF | PARP10 3984/4885NR4A2 3441/4885PTPRC 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.