Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039141 | 0.93 | CALM1 (0.55) | TAAR1CALM1CAMKK2ALDH1A1HTT | |
| SCHEMBL13889677 | 0.83 | TAAR1 (0.61) | TAAR1PYCR1AOC3ALDH1A1MCHR1 | |
| SCHEMBL13005722 | 0.81 | CALM1 (0.48) | TAAR1PYCR1AOC3CALM1CAMKK2 | |
| SCHEMBL8289786 | 0.80 | HRH3 (0.64) | TAAR1PYCR1AOC3ALDH1A1MCHR1 | |
| SCHEMBL524817 | 0.78 | CALM1 (0.65) | TAAR1AOC3CALM1CAMKK2ALDH1A1 | |
| SCHEMBL14350168 | 0.77 | TAAR1 (0.53) | TAAR1PYCR1AOC3ALDH1A1MCHR1 | |
| SCHEMBL14640185 | 0.77 | HRH3 (0.69) | TAAR1PYCR1ALDH1A1MCHR1HRH3 | |
| SCHEMBL10039133 | 0.76 | CALM1 (0.62) | PYCR1AOC3CALM1CAMKK2ALDH1A1 | |
| SCHEMBL3052863 | 0.76 | TAAR1 (1.00) | TAAR1AOC3MCHR1HRH3 | |
| SCHEMBL3191532 | 0.75 | PYCR1 (0.67) | TAAR1PYCR1AOC3ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598111-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2015-03-25 | — | — | EP | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CUTA, TYR, DSG1 | TAAR1 2784/4885PYCR1 3078/4885AOC3 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.