SCHEMBL1003958

SCHEMBL1003958

[c]1cc(-c2ccccc2)cc2c1[nH]c1ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.43
ALDH1A1 P00352 3/20 0.43
GPR3 P46089 1/20 0.43
AHR P35869 1/20 0.42
HPGD P15428 3/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
TDO2 P48775 4/20 0.41
HTR2B P41595 1/20 0.41
HTR5A P47898 1/20 0.41
KDM4E B2RXH2 3/20 0.41
CTSV O60911 1/20 0.41
LMNA P02545 1/20 0.41
TUBB4A P04350 1/20 0.41
TP53 P04637 1/20 0.41
TUBB P07437 1/20 0.41
CTSL P07711 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698660 0.95 ALDH1A1 (0.48) HSD17B10ALDH1A1GPR3AHRHPGD
SCHEMBL813579 0.88 CDK4 (0.46) KDM4EMEN1MAPTKMT2ACDK4
SCHEMBL25397447 0.83 KIF11 (0.42) TDO2HTR2BHTR5AIDO1KIF11
SCHEMBL20398830 0.76 KIF11 (0.41) HSD17B10ALDH1A1GPR3AHRHPGD
SCHEMBL11629914 0.75 KIF11 (0.56) HSD17B10ALDH1A1GPR3AHRHTT
Carbazole SCHEMBL29177816 0.74 ALDH1A1 (0.78) HSD17B10ALDH1A1GPR3AHRHPGD
Carbazole SCHEMBL51051 0.74 ALDH1A1 (0.78) HSD17B10ALDH1A1GPR3AHRHPGD
Carbazole SCHEMBL29177761 0.74 ALDH1A1 (0.78) HSD17B10ALDH1A1GPR3AHRHPGD
Carbazole SCHEMBL433857 0.74 ALDH1A1 (0.78) HSD17B10ALDH1A1GPR3AHRHPGD
SCHEMBL13387769 0.73 KIF11 (0.58) HSD17B10ALDH1A1GPR3AHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866617-A Organic electroluminescent material, light-emitting device, light-emitting panel, and light-emitting apparatus 京东方科技集团股份有限公司 2024-04-12 CN claimed
CN-108117495-B Spirofluorene ring compound, use thereof, and organic electroluminescent device using the same 北京鼎材科技有限公司 2021-11-19 CN claimed
CN-117866617-A Organic electroluminescent material, light-emitting device, light-emitting panel, and light-emitting apparatus 京东方科技集团股份有限公司 2024-04-12 CN disclosed
CN-108117495-B Spirofluorene ring compound, use thereof, and organic electroluminescent device using the same 北京鼎材科技有限公司 2021-11-19 CN disclosed
CN-111848416-B Pyrene blue fluorescence doping substance and organic electroluminescent device containing pyrene blue fluorescence doping substance 南京高光半导体材料有限公司 2021-09-14 CN disclosed
CN-111848416-A Pyrene blue fluorescence doping substance and organic electroluminescent device containing pyrene blue fluorescence doping substance 南京高光半导体材料有限公司 2020-10-30 CN disclosed
US-10636976-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-28 US disclosed
US-20170250346-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-9450194-B2 Heteroarene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-20 US disclosed
US-9040172-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-05-26 US disclosed
US-20140183504-A1 HETEROARENE DERIVATIVE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
WO-2011000455-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10636976-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device TTI1, TTI2, TERF2 HSD17B10 3693/4885ALDH1A1 2155/4885GPR3 2184/4885
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, ICMT, NUDC HSD17B10 3658/4885ALDH1A1 1717/4885GPR3 3932/4885
US-20170250346-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE TTI1, TTI2, TERF2 HSD17B10 3693/4885ALDH1A1 2155/4885GPR3 2184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.