Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040156 | 0.85 | HTR6 (0.61) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL5624294 | 0.82 | CA2 (0.59) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL10040087 | 0.80 | HTR6 (1.00) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL10040109 | 0.79 | HTR6 (0.61) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL29914888 | 0.79 | HTR6 (0.61) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL10040108 | 0.78 | HTR6 (0.74) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL15346095 | 0.77 | GAA (0.54) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL18194403 | 0.73 | CA2 (0.73) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL77876 | 0.73 | MKNK1 (0.63) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL30516501 | 0.73 | MKNK1 (0.63) | MEN1PSIP1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072882-A1 | SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-8829002-B2 | Substituted methyl amines, serotonin 5-HT6 receptor antagonists, methods for production and use thereof | IVACHTCHENKO ALEXANDRE VASILIEVICH (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829002-B2 | Substituted methyl amines, serotonin 5-HT6 receptor antagonists, methods for production and use thereof | IVACHTCHENKO ALEXANDRE VASILIEVICH (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130267536-A1 | SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130267536-A1 | SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2013-10-10 | — | — | US | disclosed |
| WO-2012087182-A2 | SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ, ЛЛС (US) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267536-A1 | SUBSTITUTED METHYL AMINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS FOR PRODUCTION AND USE THEREOF | HTR6, HTR1F, HTR1A | HTR6 1/4885CA12 4785/4885CA1 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.