SCHEMBL10040396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9359137	0.84	TRPV1 (0.52)	TDP1RAB9ANPC1TRPV1RXFP1
	SCHEMBL11737076	0.82	TDP1 (0.51)	TDP1RAB9ANPC1RXFP1POLB
	SCHEMBL10040397	0.79	TRPV1 (0.59)	RAB9ATRPV1MAPTKMT2AMEN1
	SCHEMBL6738921	0.78	IDO1 (0.56)	RXFP1
	SCHEMBL10040411	0.78	TDP1 (0.42)	TDP1RAB9ANPC1TRPV1RXFP1
	SCHEMBL10040388	0.77	MEN1 (0.48)	TDP1RAB9ANPC1TRPV1RXFP1
	SCHEMBL13588244	0.77	RAB9A (0.45)	TDP1RAB9ANPC1L3MBTL1MAPT
	SCHEMBL13588221	0.76	NPC1 (0.52)	TDP1RAB9ANPC1TRPV1RXFP1
	SCHEMBL30369173	0.76	RAB9A (0.61)	RAB9ANPC1POLBMAPTALDH1A1
	SCHEMBL194202	0.76	RAB9A (0.61)	RAB9ANPC1POLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.