SCHEMBL10040401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL998061	0.83	ELANE (0.42)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL5675873	0.82	KDM4E (0.54)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL3818138	0.77	ESR1 (0.54)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL3124521	0.77	MAPT (0.50)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL70005	0.77	PTPN22 (0.58)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL8685474	0.76	HSD17B10 (0.50)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL27940178	0.76	ERN1 (0.46)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL9125063	0.75	HSD17B10 (0.59)	PTPN22POLBCYP1A2HSD17B10CYP2C9
	SCHEMBL10236585	0.74	PTPN22 (0.50)	PTPN22POLBCYP1A2HSD17B10USP2
	SCHEMBL10040391	0.74	IDO1 (0.50)	POLBHSD17B10USP2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.