SCHEMBL10041665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6930919	0.89	TDP1 (0.55)	TDP1PTPN1ERN1S100A4MAPT
	SCHEMBL10041701	0.85	TDP1 (0.52)	TDP1PTPN1ERN1S100A4MAPT
	SCHEMBL10041658	0.85	TDP1 (0.52)	TDP1PTPN1ERN1S100A4MAPT
	SCHEMBL10921345	0.82	HSD11B1 (0.42)	TDP1PTPN1ERN1MAPTALDH1A1
	SCHEMBL1987195	0.82	TDP1 (0.48)	TDP1PTPN1ERN1S100A4MAPT
	SCHEMBL10586437	0.82	TDP1 (0.48)	TDP1ERN1S100A4ALDH1A1MEN1
	SCHEMBL2448929	0.82	TDP1 (0.48)	TDP1ERN1S100A4GABRPGABRD
	SCHEMBL1547476	0.82	TDP1 (0.52)	TDP1ERN1ALDH1A1MEN1KMT2A
	SCHEMBL10041704	0.81	TDP1 (0.57)	TDP1PTPN1ERN1S100A4MAPT
	SCHEMBL10041705	0.81	TDP1 (0.52)	TDP1ERN1S100A4MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.