Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899436 | 0.83 | PDE4D (0.39) | PDE7APDE4DNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL899437 | 0.83 | PDE4D (0.39) | PDE7APDE4DNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL899381 | 0.82 | MAPT (0.41) | PDE7APDE4DSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL899306 | 0.81 | MAPT (0.46) | NPSR1MAPK1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL899307 | 0.81 | MAPT (0.46) | NPSR1MAPK1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL899582 | 0.80 | SMN1; SMN2 (0.42) | PDE7APDE4DNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL899584 | 0.80 | SMN1; SMN2 (0.42) | PDE7APDE4DNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL899218 | 0.72 | PDE4D (0.38) | PDE7APDE4DNPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL903016 | 0.71 | ALDH1A1 (0.40) | NPSR1MAPK1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2435561 | 0.67 | TSHR (0.52) | NPSR1MAPK1SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |