Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947174 | 0.81 | NPC1 (0.75) | NPC1RAB9AGFERHDAC3HDAC1 | |
| SCHEMBL2706413 | 0.80 | NPC1 (0.49) | NPC1RAB9AGFERFBP1HDAC3 | |
| SCHEMBL4399183 | 0.80 | L3MBTL1 (0.53) | NPC1RAB9AGFERFBP1HDAC3 | |
| SCHEMBL15745637 | 0.79 | NPC1 (0.73) | NPC1RAB9AGFERHDAC3HDAC1 | |
| SCHEMBL3288472 | 0.79 | NPC1 (0.78) | NPC1RAB9AGFERHDAC3HDAC1 | |
| SCHEMBL10045308 | 0.79 | NPC1 (0.68) | NPC1RAB9AGFERHDAC3HDAC1 | |
| SCHEMBL23095285 | 0.79 | NPC1 (0.48) | NPC1RAB9AGFERFBP1HDAC3 | |
| SCHEMBL179531 | 0.79 | MAPT (0.56) | NPC1RAB9AGFERFBP1HDAC3 | |
| SCHEMBL3068277 | 0.79 | FBP1 (0.50) | NPC1RAB9AGFERFBP1HDAC3 | |
| SCHEMBL29594055 | 0.79 | NPC1 (0.48) | NPC1RAB9AGFERFBP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8120022-B2 | Light emitting device material and light emitting device | TORAY INDUSTRIES, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8120022-B2 | Light emitting device material and light emitting device | TORAY INDUSTRIES, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100187520-A1 | LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE | LEF1, CRY1, SOD1 | NPC1 2107/4885RAB9A 425/4885GFER 1844/4885 |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PPARA, PPARG, PPARD | NPC1 59/4885RAB9A 2271/4885GFER 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.