Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899268 | 0.82 | KCNA3 (0.37) | ALDH1A1KDM4EKCNA3LIMK1SMN1; SMN2 | |
| SCHEMBL899302 | 0.82 | CCNE1 (0.42) | ALDH1A1KDM4EKCNA3RAB9AHPGD | |
| SCHEMBL899508 | 0.82 | HDAC1 (0.47) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL10045107 | 0.78 | LIMK1 (0.39) | ALDH1A1KDM4EKCNA3LIMK1TSHR | |
| SCHEMBL899484 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EKCNA3RAB9AHPGD | |
| SCHEMBL899084 | 0.76 | KCNH2 (0.38) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL899366 | 0.76 | HSD17B2 (0.46) | RAB9ANPC1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL903025 | 0.75 | HDAC1 (0.40) | ALDH1A1KDM4ETSHRCYP3A4MLYCD | |
| SCHEMBL902944 | 0.72 | HDAC1 (0.38) | ALDH1A1KDM4ETAAR1 | |
| SCHEMBL22292768 | 0.71 | GAA (0.41) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |