Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899084 | 0.90 | KCNH2 (0.38) | CCNE1CDK2CDK5KDM4EALDH1A1 | |
| SCHEMBL899508 | 0.90 | HDAC1 (0.47) | CCNE1CDK2CDK5KDM4EALDH1A1 | |
| SCHEMBL903025 | 0.89 | HDAC1 (0.40) | CCNE1CDK2CDK5KDM4EALDH1A1 | |
| SCHEMBL899366 | 0.87 | HSD17B2 (0.46) | HDAC1NPC1LMNARAB9A | |
| SCHEMBL899467 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1NPC1LMNARAB9A | |
| SCHEMBL902944 | 0.83 | HDAC1 (0.38) | KDM4EALDH1A1USP30HDAC1TAAR1 | |
| SCHEMBL899484 | 0.83 | ALDH1A1 (0.38) | KDM4EALDH1A1KCNA3NPC1LMNA | |
| SCHEMBL10045592 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1KCNA3TAAR1NR3C2 | |
| SCHEMBL899268 | 0.80 | KCNA3 (0.37) | KDM4EALDH1A1KCNA3TAAR1NR3C2 | |
| SCHEMBL10045107 | 0.78 | LIMK1 (0.39) | KDM4EALDH1A1KCNA3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | claimed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |