Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899302 | 0.90 | CCNE1 (0.42) | HDAC1KDM4EALDH1A1KDRNPC1 | |
| SCHEMBL899084 | 0.87 | KCNH2 (0.38) | HDAC1KDM4EALDH1A1ACKR3NPC1 | |
| SCHEMBL899366 | 0.86 | HSD17B2 (0.46) | HDAC1ACKR3NPC1LMNARAB9A | |
| SCHEMBL903025 | 0.86 | HDAC1 (0.40) | HDAC1KDM4EALDH1A1CYP3A4CCNE1 | |
| SCHEMBL902944 | 0.82 | HDAC1 (0.38) | HDAC1KDM4EALDH1A1 | |
| SCHEMBL10045592 | 0.82 | ALDH1A1 (0.39) | CYP2C19KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL899484 | 0.77 | ALDH1A1 (0.38) | CYP2C19KDM4EALDH1A1MEN1HTT | |
| SCHEMBL899467 | 0.77 | ALDH1A1 (0.44) | CYP2C19KDM4EALDH1A1ACKR3HTT | |
| SCHEMBL899268 | 0.74 | KCNA3 (0.37) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28539999 | 0.73 | KDR (0.46) | HDAC1KDM4EALDH1A1KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |