Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899302 | 0.83 | CCNE1 (0.42) | HDAC1KDM4EALDH1A1TAAR1USP30 | |
| SCHEMBL899508 | 0.82 | HDAC1 (0.47) | HDAC1KDM4EALDH1A1 | |
| SCHEMBL899366 | 0.81 | HSD17B2 (0.46) | HDAC1 | |
| SCHEMBL903025 | 0.81 | HDAC1 (0.40) | HDAC1KDM4EALDH1A1 | |
| SCHEMBL899084 | 0.80 | KCNH2 (0.38) | HDAC1KDM4EALDH1A1 | |
| SCHEMBL10045592 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1TAAR1 | |
| SCHEMBL899467 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL899484 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL899268 | 0.68 | KCNA3 (0.37) | KDM4EALDH1A1TAAR1 | |
| SCHEMBL10045107 | 0.67 | LIMK1 (0.39) | KDM4EALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |