Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045107 | 0.83 | LIMK1 (0.39) | KCNA3ALDH1A1KDM4ELIMK1TSHR | |
| SCHEMBL10045592 | 0.82 | ALDH1A1 (0.39) | KCNA3ALDH1A1KDM4ELIMK1MLYCD | |
| SCHEMBL899302 | 0.80 | CCNE1 (0.42) | KCNA3ALDH1A1KDM4EMLYCDTAAR1 | |
| SCHEMBL899084 | 0.80 | KCNH2 (0.38) | ALDH1A1KDM4EMLYCDTSHRGAA | |
| SCHEMBL899484 | 0.75 | ALDH1A1 (0.38) | KCNA3ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL899508 | 0.74 | HDAC1 (0.47) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL903025 | 0.73 | HDAC1 (0.40) | ALDH1A1KDM4EMLYCDTSHRCYP19A1 | |
| SCHEMBL899366 | 0.72 | HSD17B2 (0.46) | TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL898826 | 0.70 | XDH (0.48) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL22292768 | 0.69 | GAA (0.41) | ALDH1A1KDM4ETSHRGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | claimed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |