Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | HTR3A | P46098 | 11/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004616 | 1.00 | OPRD1 (0.39) | OPRD1HTR3ACYP2C19KDM4ECYP1A2 | |
| SCHEMBL1004578 | 1.00 | OPRD1 (0.39) | OPRD1HTR3ACYP2C19KDM4ECYP1A2 | |
| SCHEMBL1007536 | 0.90 | OPRD1 (0.43) | OPRD1HTR3A | |
| SCHEMBL1007535 | 0.90 | OPRD1 (0.43) | OPRD1HTR3A | |
| SCHEMBL1007691 | 0.90 | OPRD1 (0.43) | OPRD1HTR3A | |
| SCHEMBL1006137 | 0.81 | HTR3A (0.66) | HTR3ACYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL1005871 | 0.80 | HTR3A (0.65) | HTR3ACYP2C19KCNH2 | |
| SCHEMBL3987869 | 0.77 | NAAA (0.39) | HTR3AKCNH2 | |
| SCHEMBL1005698 | 0.76 | HTR3A (0.47) | HTR3AKCNH2 | |
| SCHEMBL1005699 | 0.76 | HTR3A (0.47) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863271-B2 | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | AMR TECHNOLOGY, INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | HTR3E, HTR3C, HTR3A | OPRD1 109/4885HTR3A 3/4885CYP2C19 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.