SCHEMBL1004592 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	6/20	0.37

▸	ANPEP	P15144	5/20	0.37

▸	KMT2A	Q03164	1/20	0.35

▸	BRD4	O60885	1/20	0.34

▸	CYP1A2	P05177	1/20	0.33

▸	HIF1A	Q16665	1/20	0.33

▸	P2RX7	Q99572	1/20	0.31

▸	CYP3A4	P08684	2/20	0.30

▸	MAPT	P10636	2/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1003643	0.83	PTPN1 (0.38)	MMP2ANPEPBRD4P2RX7CYP3A4
SCHEMBL1006401	0.78	MMP2 (0.36)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL1007354	0.70	FKBP1A (0.39)	MMP2ANPEPKMT2AMAPT
SCHEMBL13739598	0.69	KMT2A (0.49)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL29388224	0.69	KMT2A (0.49)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL17136885	0.66	MMP2 (0.41)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL13738649	0.65	MMP2 (0.37)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL17136874	0.65	ACE (0.46)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL17448552	0.65	MMP2 (0.37)	MMP2ANPEPKMT2ABRD4CYP1A2
SCHEMBL17442799	0.64	DRD2 (0.55)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011011330-A2	INHIBITORS OF D-AMINO ACID OXIDASE	SEPRACOR INC. (US)	2011-01-27	—	—	WO	disclosed